The nucleus is a conserved mechanosensation and mechanoresponse organelle

Editorial overview: Cell nucleus: the nucleus: a dynamic organelle.

The nucleus is perhaps the defining feature of ‘eukaryotes’ (Greek ‘eu-’ (with) ‘-karyon’ (kernel, nucleus)), and the emperor of all eukaryotic organelles in terms of scale and complexity of organization. It is, of course, the repository for almost all genomic information, encoded in DNA sequences wrapped into chromatin as discrete polymer packages termed chromosomes, surrounded in turn by a do...

the investigation of the relationship between type a and type b personalities and quality of translation

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Organelle Signaling: How Stressed Chloroplasts Communicate with the Nucleus

Plastids are able to relay information to the nucleus to regulate stress responses. A new genetic screen has identified an isoprenoid intermediate that accumulates in stressed plastids and acts as a novel retrograde signal.

Mechanosensation is evolutionarily tuned to locomotor mechanics.

The biomechanics of animal limbs has evolved to meet the functional demands for movement associated with different behaviors and environments. Effective movement relies not only on limb mechanics but also on appropriate mechanosensory feedback. By comparing sensory ability and mechanics within a phylogenetic framework, we show that peripheral mechanosensation has evolved with limb biomechanics,...

Cardiac Myocytes and Mechanosensation